ACCIDENTAL HIGH-DOSE EXTRADURAL MORPHINE
نویسندگان
چکیده
منابع مشابه
Dose-effect relationships of extradural morphine.
The effectiveness of three different doses of extradural morphine (4, 6 and 8 mg) in relieving post-operative pain was compared in 24 patients. Although there was no significant difference in the efficacy of the three doses, increasing dosage increased the average duration of analgesia provided by the drug (4 mg--593 min; 6 mg--772 min; 8 mg--885 min). All three doses increased the average peak...
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on ketamine requirement. Following atropine premedication ketamine 5 mg lb" was administered i.m. They found that i.v. supplementation was required to prevent limb movement before surgery in 70% of patients less than 1 year of age and showed that i.v. ketamine requirements for surgical anaesthesia were associated with age, weight and surface area, age being most significant: i.v. ketamine (ng l...
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A case of accidental administration of high dose intrathecal diamorphine is reported in a patient who underwent total knee replacement. Initially a regional technique was planned for this patient, but due to inadvertent administration of three milligrams of diamorphine intrathecally, it was decided to convert the patient to have a general anaesthetic. Postoperatively, she was monitored in high ...
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In in vitro studies, macrophage morphine priming (MP; preincubation with low-dose morphine) attenuated the effects of high-dose morphine (HDM) on macrophage capabilities of killing and containment of phagocytosed bacteria. In in vivo studies, mice received either normal saline (control), HDM, or MP twice daily for 10 consecutive days. All HDM-treated mice showed a significant peritoneal bacteri...
متن کاملExperimental comparison of extradural and i.m. morphine.
Morphine sulphate 3 or 4 mg was administered to the extradural space in five volunteers. Morphine 10 or 15 mg i.m. was given as control. Extradural administration resulted in an increase of pain threshold in the legs but not in the forehead. There was no significant depression of carbon dioxide response or deterioration of co-ordination or short-term memory. I.m. morphine caused an increase in ...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1982
ISSN: 0007-0912
DOI: 10.1093/bja/54.11.1237-b